Rising Trends in High-Dose Biotin Supplement Use and Its Impact on Lab Testing Accuracy

A recent JAMA study highlights a significant rise in biotin supplement use among U.S. adults from 1999 to 2016. Biotin, a B vitamin popular for its purported benefits to hair, skin and nails, has seen increased consumption at dosages far exceeding the recommended daily allowance, with many people taking 1 mg or more daily, and a notable portion consuming 5 mg or higher.

Key findings reveal that women and older adults are more likely to take high-dose biotin supplements. However, the study warns that excessive biotin intake can interfere with various lab tests, including those assessing thyroid function and cardiac markers, leading to possible misdiagnosis or inappropriate treatment.

The article underscores the importance of healthcare providers asking patients about supplement use, especially biotin, when interpreting lab results to avoid errors. Public awareness about the potential risks of high-dose biotin remains limited, despite its widespread use.

This trend has crucial implications for clinicians, laboratories, and patients, emphasizing the need for improved education on supplement impacts and careful testing protocols to ensure accurate diagnostics. The growing popularity of biotin supplements calls for vigilance among healthcare professionals to safeguard patient safety and care quality.

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